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KMID : 0361020110540030185
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Korean Journal of Otolaryngology - Head and Neck Surgery
2011 Volume.54 No. 3 p.185 ~ p.191
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Clinical Application of Nanotechnology
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Baek Seung-Kuk
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Abstract
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The limitations of current modalities for diagnosis and treatment of various diseases including cancer have led to look for the method with more sensitivity or specificity and lower toxicity. The advance in nanobiotechnology has shown the possibility to get newer and improved diagnostic and treatment method. Especially, gold nanoparticles can be applied diagnostically for early detection of cancer cells by molecular imaging or therapeutically for drug delivery, including chemotherapeutic drugs, photothermal therapy, and ionizing radiation enhancement. This review discusses characteristics, action mechanisms, and clinical application of nanoparticle. Even if the safety of nanoparticles is not yet fully defined, there is no doubt that nanotechnology in the future may play an important role in the diagnosis and treatment of various human diseases. Korean J Otorhinolaryngol-Head Neck Surg 2011;54:185-91
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KEYWORD
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Nanotechnology, Nanoparticles, Drug delivery systems, Laser therapy
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